by David Wu | Nov 7, 2021 | Uncategorized
New manuscript in press at PNAS!! Targeted polyelectrolyte complex micelles treat vascular complications in vivo. Zhengjie Zhou1,2, Chih-Fan Yeh2,3, Michael Mellas1, Myung-Jin Oh2, Jiayu Zhu2, Jin Li2, Ru-Ting Huang2, Devin Harrison2.4, Tzu-Pin Shentu2, David Wu2,...
by David Wu | Sep 10, 2021 | Uncategorized
Single-cell lactate production rate as a measure of glycolysis in endothelial cells https://star-protocols.cell.com/protocols/986 Summary Heterogeneous metabolism supports critical single-cell functions. Here, we describe deep-learning-enabled image analyses of a...
by David Wu | Sep 5, 2021 | Uncategorized
Devin and Dave’s paper detailing the methods we used for quantifying single cell metabolism in endothelial cells. Congrats, Devin! Devin Harrison*, David Wu*, Jun Huang, Yun Fang. Single-cell lactate production rate as a measure of glycolysis in endothelial...
by David Wu | Sep 5, 2021 | Uncategorized
Congratulations to Jin Li for her fantastic review! Jin Li, Yun Fang* and David Wu*. Mechanical forces and metabolic changes cooperate to drive cellular memory and endothelial phenotypes. Current Topics in Membranes: Cellular Mechanostransduction Mechanisms to...
by David Wu | Aug 25, 2021 | Uncategorized
We welcome Yun Shi, PhD, as a new post-doctoral scholar to the lab! Looking forward to great scientific adventures ahead..
by David Wu | Jun 9, 2021 | Uncategorized
For the first time, researchers visualize metabolic process at the single-cell level https://pme.uchicago.edu/news/first-time-researchers-visualize-metabolic-process-single-cell-level PME researchers have measured glycolysis at both the cellular and sub-cellular...
by David Wu | May 25, 2021 | Uncategorized
Formally published! Citation: Wu, D., Harrison, D.L., Szasz, T. et al. Single-cell metabolic imaging reveals a SLC2A3-dependent glycolytic burst in motile endothelial cells. Nat Metab 3, 714–727 (2021). https://doi.org/10.1038/s42255-021-00390-y with commentary as...
by David Wu | Feb 9, 2021 | Uncategorized
Now recruiting – looking for excited, energized post docs and grad students! Skills and fields, used and learned: cell biology, cloning, CRISPR, super resolution microscopy, metabolism, vascular biology. Please inquire if interested (see contact page)
by wulab | Nov 5, 2020 | Uncategorized
Welcome to the Wu Lab in the Section of Pulmonary and Critical Care in the Department of Medicine at the University of Chicago. We plan to study the metabolism of single cells as a function of mechanotransduction. Looking for post-docs and graduate students! Any...